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Description
Answered: 4. The molecular structure of the last 12 amino acid residues (dodecapeptide) that comprise the C terminal segment of semaglutide is shown below. H3N* NH NH bartleby SpaDerma Semaglutide Tirzepatide GLP 1 The treatment has been touted as a challenger to Ozempic, but experts are issuing a serious warning. Reflections on the discovery GLP 1 as a satiety hormone: Implications for obesity therapy and future directions European Journal of Clinical Nutrition Repurposing of semaglutide by targeting SIRT1 and TGF Smad signaling in hepatic fibrosis Naunyn Schmiedeberg's Archives of Pharmacology Springer Nature Link
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4.6 ★★★★★
Based on 9 reviews
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Product Reviews
★★★★★ 5
Best cream ever!
I really love this “Simple” gel cream I hope they never stop making it. I have oily skin and other creams seem to just Irritate my skin or just feel thick and heavy like it’s blocking my pores. Not this cream. It feels light weight and yet moisturizing. It has no scent. I use it all over my face and my neck. I have bought department store moisturizers and yet I keep coming back to this Simple hydrating gel cream it never fails me. The only problem is I discovered I can’t find it in any of the stores anymore in my area, I don’t know why but I never thought to look for it here on Amazon. So now I’m a faithful purchaser of this product here on Amazon I love it so much I just hope the company still will continue to make it and that Amazon will continue to sell it.
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Reviewed in the United States on May 6, 2021
★★★★★ 5
Is this the CURE!
Size: Regular, Color: Cream
I have a skin disease called Ichthyosis Vulgaris. Yes, SCALEY FISH! Thanks MOM! This unfortunate crud leaves my heels an embarrassing mess! They are cracked and dry and literally like concrete. I have had this disease all my life and there is NO cure. It's hideous! Anyway, I have tried so many different experiments to help improve my situation. So much time and money I will never get back. So when I saw these, I had to give them a try too because I am a forever optimist and love being disappointed. Here's how it went.
First I put my dermatologist recommended AmLactin on my crusty heels. Then, I put the socks on. By the way, with no problem at all, and went to bed. I was not too hot, which is usually what happens when I sleep with socks on. I never even realized that I had them on. When I woke up, I took them off and immediately used a "Heel File" over a towel removing all the yuck!. Then, I sand papered them to smooth the skin out. Then, I doused them with Shea and Aloe foot lotion I found at the bottom of my experiment drawer in my bathroom. Oh, they felt like someone else's feet. I am very hopeful at this moment! Is this the cure to my embarrassing situation? I sure hope so. Spring is here and I would really like to wear my cute flip-flops when I go to the Waffle House and set at the bar. Wasn't that a picture on Facebook of someone nasty heels? It made me gag. Then, I had to make sure that picture wasn't me! I am going to do this for a week and come back for another review. Wish me luck ya'll!
UPDATE!
So it’s been about two weeks. I wish that I had taken a before and after picture. I guess I figure that this too will be a waste of money. NO! These little socks are a God send for me. I did buy AmLactin foot repair cream and that I highly recommend. It’s the best so far. They also offer an option with heel socks. They are soft and work very well also but one negative. They leave fuzzies on you feet and tools. Guys this is it for me. My search is over! I went to my mani/pedi queen yesterday and she was shocked when she saw my feet. She is spreading the word!
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Reviewed in the United States on March 23, 2025
★★★★★ 5
Great reusable moisturizing
Size: Regular, Color: Cream
Love these! Use them often to help moisturize my heels with my favorite moisturizer. Comfortable and easy to use
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Reviewed in the United States on May 21, 2026
★★★★★ 5
Buy these!
Size: Regular, Color: Cream
I only write a review when I have a strong opinion and want to help others decide. I've been having trouble with cracked heels for months. Previously I had just been using regular socks, but these slip-ons have been game changers! They don't make my feet hot at night. They are comfortable and in the morning my heels feel soft, and I don't need to use them everyday. They look good and fit well even if I want to wear them under socks or in shoes during the day. They really do help if you have cracked heels along with some kind of lotion. Definitely effective!
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Reviewed in the United States on May 19, 2025
★★★★★ 5
Cracked heels are gone after 5 applications
Size: Regular, Color: Cream
These moisturizing socks work great. My heels are happy again. The open toe design makes it so my feet don’t overheat at night. It only took 5 times to get rid of my painful cracked heels. Now I wear them 1-2 times a week to keep my heels healthy.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 6, 2026
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