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From R&D to application: GLP 1 purification strategy Bestchrom NICE Updates Type 2 Diabetes Guidelines: Metformin + SGLT2i First Line Treatment Robert Gabbay MD, PhD posted on the topic LinkedIn Appetite effects from GLP 1 receptor compounds are based on reaching a therapeutic exposure that influences insulin secretion and slows gastric emptying. This is all dependent on GLP 1 receptor sensitivity (remember these compounds You can support GLP 1 naturally with food but let's be real Most people aren't consistent enough to get results That's why I added something simple to help support it daily The Cardiovascular Biology of Glucagon like Peptide 1: Cell Metabolism
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4.2 ★★★★★
Based on 24 reviews
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Product Reviews
★★★★★ 5
Hard diameter to find
I took a chance on these ropes being the right size diameter for my English Bulldog. So many times in pet stores they either have just the huge diameter for the large breed dogs or the very small diameter and length for the little dogs. These were perfect and a great value getting two ropes of the same size.
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Reviewed in the United States on January 14, 2026
★★★★★ 5
Great value for my money.
Strong and durable and just the right length my puppy can't bite my hand while playing with him
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Reviewed in the United States on April 28, 2026
★★★★★ 5
These are NOT meant for regular play like the other reviews seem to think.
First things first, ignore 90% of these reviews. The reviews saying these balls didn’t last very long clearly don’t know what they’re meant for. These are not “drop and play” kinds of toys. They’re meant to be used as reward toys. Meaning they get used during training sessions for a quick game of tug to reward the dog for good behavior. These are NOT meant for unsupervised play, and not meant for dogs who don’t have reliable recall or drop/Aus commands.
That being said, my dog is 95 pounds and stands 29” at the shoulder. She’s a big girl who plays rough. Immediately after opening the package, we did a quick training session with these reward toys. They held up EXTREMELY well. They are made of rubber which means she doesn’t shred them in one short game of tug unlike some of the foam reward toys you will come across. I did have to tighten the knot below the ball before using them, but that’s to be expected with any rope style toy.
If your dog does not have a reliable drop command and they are any larger than maybe 25lbs, I would not suggest using the smaller ball. If Nikita didn’t have a reliable drop command, it would be incredibly easy for her to wind up choking on the smaller ball. Even the large ball is pushing it on choking hazard size for a large dog, but again, reliable drop commands are important.
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Reviewed in the United States on August 6, 2020
★★★★★ 5
Good quality. 3 month review
My dog likes them more than the more expensive versions we have. Still in one piece and they get beat on, tugged with me and a dog or by 2 dogs both about 70lbs
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Reviewed in the United States on April 1, 2026
★★★★★ 3
Dog doesn’t like how it slams into his face from the weight
The balls were heavier than I expected and my dog does not like to engage with it even when I drag and throw them around to play with. To heavy duty for cattle dog
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Reviewed in the United States on October 5, 2025
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